Who Is at Risk for Oral Herpes

Who Is at Risk for Oral Herpes Oral herpes is usually caused by HSV-1. The highest incidence of first infection occurs between 6 months and 3 years of age. The incidence in children varies among regions and countries, with the highest rates occurring in crowded and unsanitary regions. Studies suggest that by age 5 more than a third of children in low-income areas are infected compared to 20% of children in middle-income areas. However, by the time Americans of all economic backgrounds reach age 60, about 60 – 85% have become infected with HSV-1.